Impact of the COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, Version 1.5, on Clinical Laboratory Operations
نویسندگان
چکیده
منابع مشابه
Comparison of the COBAS/Ampliprep Taqman and Amplicor HIV-1 monitor tests in Lagos, Nigeria
BACKGROUND The use of real-time Polymerase chain reaction (PCR) technology options is increasing in resource-limited settings because they are faster, improve assay sensitivity, have higher throughput, larger dynamic ranges and reduced rates of contamination. In 2010, UNAIDS ranked Nigeria as the second highest population of people living with HIV and AIDS (2.98 million people) in the world. ...
متن کاملClinical evaluation of the automated COBAS AMPLICOR HCV MONITOR test version 2.0 for quantifying serum hepatitis C virus RNA and comparison to the quantiplex HCV version 2.0 test.
A second-generation hepatitis C virus (HCV) quantitative assay (COBAS AMPLICOR HCV MONITOR Test, version 2.0; COBAS HCM-2) has been developed, with the intention of achieving equivalent quantification of all HCV genotypes and improving assay performance. To evaluate the clinical performance of COBAS HCM-2 and its utility in predicting the response to alpha interferon treatment, sera from 215 ch...
متن کاملPerformance of the automated COBAS AmpliPrep/COBAS TaqMan HIV-1 test on a genetically diverse panel of specimens from China: comparison to the COBAS amplicor HIV-1 monitor test, v1.5.
OBJECTIVES To investigate the impact of genetically diverse HIV samples from China on the performance of the automated COBAS(R) AmpliPrep/COBAS TaqMan(R) HIV-1 Test (CAP/CTM). METHODS 185 samples from untreated HIV-1-infected patients were used to assess the performance of the CAP/CTM Test and COBAS Amplicor HIV-1 Monitor Test, v1.5 (Cobas). RESULTS A comparison of the qualitative results o...
متن کاملComparison of the Cobas Ampliprep/Cobas TaqMan HBV Test versus the Cobas Amplicor HBV monitor for HBV-DNA detection and quantification during antiviral therapy.
Performances of the new automatic system COBAS AmpliPrep/COBAS TaqMan 48 (CAP/CTM) (Roche, Branchburg, NJ) for HBV DNA extraction and real-time PCR quantification were assessed and compared with the endpoint PCR COBAS AMPLICOR HBV Monitor (CAHBM, Roche). Analytical evaluation with proficiency panels from UK National External Quality Assessment Scheme (UK NEQAS) over a 1-year period of distribut...
متن کاملAssessment of viral loads in patients with chronic hepatitis C with AMPLICOR HCV MONITOR version 1.0, COBAS HCV MONITOR version 2.0, and QUANTIPLEX HCV RNA version 2.0 assays.
The correlation between response to antiviral therapy and pretreatment viral load in patients with chronic hepatitis C has prompted the development of quantitative assays to measure viral load. The aim of our study was to assess the clinical relevance of the newly developed semiautomated PCR system COBAS HCV MONITOR version 2.0 in comparison with (i) the AMPLICOR HCV MONITOR version 1.0 assay, ...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2007
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.00656-07